Year: 2019

In recent years, the concept of “small vascular disease” has been distinguished, as causes of a decrease in coronary reserve and the appearance of myocardial ischemia, which is often observed with a combination of hypertension,

As in other areas of clinical medicine, success in treating patients with diabetes mellitus and arterial hypertension depends largely on how wisely the doctor and patient use the abilities to control the disease. Optimal metabolic

The report of the 4th Joint National Committee on detection, evaluation and treatment of high blood pressure medication recommended to start with the destination of any of the diuretics Cove, adrenoblokatorov ( -blockers), Ca antagonists (calcium channel

The antianginal activity of drugs in this group is slightly lower than that of calcium antagonists. In some cases, there is evidence of the occurrence of myocardial ischemia by the mechanism of “stealing”. At the same time,

The newest class of antihypertensive drugs synthesized in the early 1990s. These compounds block the renin-angiotensin cascade on the periphery, acting directly in the location of the receptors, that is, in the vascular wall, and do

Diuretics have been used successfully for the treatment of hypertension since the mid-1950s. The exact mechanism of the hypotensive action of diuretics is unknown, despite the fact that they have been used for this purpose

In patients with diabetes mellitus, diuretics in arterial hypertension are rarely used as monotherapy, more often in combination with drugs of the considered groups. Among the various classes of diuretics (thiazide, loop, potassium-saving, osmotic) it

Calcium channel blockers or calcium antagonists. All calcium antagonists are very powerful peripheral vasodilators and deplete blood pressure, reducing OPS . Preparations of this group have a specific ability to inhibit the penetration of calcium ions into smooth

Blockers of  – adrenergic receptors inhibit the effects of  – adrenergic stimuli on various organs. Stimulation of the  – receptors leads to renin release, vasodilation, bronchodilatation, an increase in cardiac output and pulse; increased insulin secretion, glycogenolysis, gluconeogenesis in the liver

Drugs of this class are now rarely used, mainly due to the emergence of new, better tolerated drugs. Two drugs, guanethidine (Ismelin) and guanadrel (Gilorel) , however, are very effective and inhibit the activity of the sympathetic