The clinic of the lesion of the cardiovascular system is caused by the duration and severity of hypothyroidism. The greatest changes come to light at expressed and it is long current forms. Changes in the cardiovascular
Gastrointestinal
When hypothyroidism develops atrophy and edema of the mucous membrane of the stomach and intestines, as well as reduced motor function of the gastrointestinal tract. Clinically, this is manifested by chronic gastritis (loss of appetite, a
Endocrine glands
Hypothyroidism patients often show signs of damage to many endocrine glands. There is a decrease in the functional reserves of the hypothalamic-pituitary-adrenal system. Characterized by a decrease in the formation of cortisol and a decrease in
Hypothyroid coma
Hypothyroid coma is an extremely severe manifestation of hypothyroidism, characterized by the most acute exacerbation of all symptoms of the disease and loss of consciousness. The main reasons leading to the development of hypothyroid coma:
Regulation of water-salt metabolism
Maintaining the tone of the extracellular fluid in a very narrow range is extremely important for the full function of the cells of the body. Extracellular osmolarity regulates both the shape of the cell and
Osmoreceptor system
About ne of the most important factors in the regulation of secretion of vasopressin is the plasma osmolality. Osmoreceptors located in the hypothalamus are extremely sensitive to changes in plasma osmolarity. Increasing its level by only
Renin-angiotensin-aldosterone system
In addition to the mechanisms of the osmotic sensor and effector, water-salt metabolism in the human body is regulated by the mechanisms of the volumetric sensor and effector, the main of which is the renin-angiotensin-aldosterone
Central diabetes insipidus
Etiology Diabetes mellitus develops due to inadequate synthesis and / or secretion of antidiuretic hormone (central form), or the inability of the kidneys to respond adequately to circulating vasopressin (renal form). In endocrinological practice, diabetes
Etiology Diabetes mellitus develops due to inadequate synthesis and / or secretion of antidiuretic hormone (central form), or the inability of the kidneys to respond adequately to circulating vasopressin (renal form). In endocrinological practice, diabetes
Neurosurgical interventions
One of the most common causes of central diabetes insipidus in children is the neurosurgical destruction of vasopressin neurons after surgery on the hypothalamic-pituitary area. It is important to distinguish polyuria associated with postoperative central
Infiltrative, autoimmune and infectious diseases
Histiocytosis of Langerhans cells and lymphocytic hypophysitis are the most common infiltrative diseases causing diabetes insipidus. About 10% of patients with histocytosis have diabetes insipidus diabetes, and polyuria may precede the detection of intracranial damage
Histiocytosis of Langerhans cells and lymphocytic hypophysitis are the most common infiltrative diseases causing diabetes insipidus. About 10% of patients with histocytosis have diabetes insipidus diabetes, and polyuria may precede the detection of intracranial damage